MAP1LC3A

GENERAL INFORMATION

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Gene name

MAP1LC3A

Gene description

Microtubule-associated protein 1 light chain 3 alpha

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression abundant in neuronal cells.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation. Caution, targets protein from more than one gene.

Data reliability

Supportive based on 4 antibodies.
HPA007649 , HPA052474 , HPA052484 , CAB037174
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

MAP1LC3A (HGNC Symbol)

Synonyms

ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3

Description

Microtubule-associated protein 1 light chain 3 alpha (HGNC Symbol)

Entrez gene summary

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012]

Chromosome

20

Cytoband

q11.22

Chromosome location (bp)

34546854 - 34560345

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101460 (version 78.38)

Entrez gene

84557

UniProt

Q9H492 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H492

Antibodypedia

MAP1LC3A antibodies


PROTEIN BROWSER

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ENST00000360668
 
ENST00000374837
 
ENST00000397709
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAP1LC3A-001 ENSP00000363970
ENST00000374837
Q9H492
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Show » Show » 125 14.5 No 0
MAP1LC3A-002 ENSP00000353886
ENST00000360668
Q9H492
Show all »
Show » Show » 121 14.3 No 0
MAP1LC3A-003 ENSP00000380821
ENST00000397709
Q9H492
Show all »
Show » Show » 121 14.3 No 0