Tissue expression of BDNF - Summary - The Human Protein Atlas

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BDNF

TISSUE

SUBCELL

CELL LINE

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN ANTIBODY/ANTIGEN


Dictionary

GENERAL INFORMATION ? »
Protein class Protein class the gene product belongs to according to selected gene lists. List of protein classes. Predicted localization Protein localization predicted from several bioinformatic algorithms. More info... Number of transcripts Number of protein-coding transcribed from this gene as defined by Ensembl.
Gene name	BDNF
Gene description	Brain-derived neurotrophic factor
Protein class	Cancer-related genes Disease related genes Plasma proteins Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins
Predicted localization	Intracellular,Membrane,Secreted
Number of transcripts	17
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:	Tissue enhanced (cerebral cortex)
GTEx:	Tissue enhanced (cerebellum)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression mainly in CNS.

ANTIBODY RELIABILITY ? »
Data reliability description Standardized explanatory sentences with additional information required for full understanding of the knowledge-based expression profile. Currently, not all genes have been analyzed by knowledge-based annotation, indicated by "Pending RNA-based expert annotation", when applicable. Data reliability Data reliability score (score description), divided into supportive (premium) or uncertain (not premium), is based on consistency between the staining pattern of one antibody or several antibodies with RNA-seq data and available gene/protein characterization data.
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex. Pending retesting.
Data reliability	Uncertain based on 1 antibody. CAB009564
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Lateral ventricle

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

N/A

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

N/A

Prostate

Seminal vesicle

N/A

Female tissues

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

PROTEIN EXPRESSION OVERVIEW

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Organ

Expression

RNA EXPRESSION OVERVIEW

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HPA dataset

RNA tissue category:

Tissue enhanced (cerebral cortex)

Organ

Expression

GTEx dataset

RNA tissue category:

Tissue enhanced (cerebellum)

Organ

Expression

GENE INFORMATION ? »
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Gene name	BDNF
Synonyms
Description	Brain-derived neurotrophic factor (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]
Chromosome	11
Cytoband	p14.1
Chromosome location (bp)	27654893 - 27722058
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000176697 (version 78.38)
Entrez gene	627
UniProt	P23560 (UniProt - Evidence at protein level)
neXtProt	NX_P23560
Antibodypedia	BDNF antibodies

PROTEIN BROWSER

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ENST00000314915		ENST00000356660		ENST00000395978		ENST00000395980		ENST00000395981		ENST00000395983		ENST00000395986		ENST00000418212		ENST00000420794		ENST00000438929		ENST00000439476		ENST00000525528		ENST00000525950		ENST00000530861		ENST00000532997		ENST00000533131		ENST00000533246

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)	Transmembrane regions (predicted)
BDNF-001	ENSP00000432035 ENST00000525950	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-002	ENSP00000379305 ENST00000395981	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-003	ENSP00000379302 ENST00000395978	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-004	ENSP00000435805 ENST00000532997	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-007	ENSP00000379307 ENST00000395983	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-008	ENSP00000414303 ENST00000438929	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:21%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:14%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:9%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0001657 [ureteric bud development] GO:0001662 [behavioral fear response] GO:0001666 [response to hypoxia] GO:0002544 [chronic inflammatory response] GO:0005102 [receptor binding] GO:0005169 [neurotrophin TRKB receptor binding] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0005737 [cytoplasm] GO:0006120 [mitochondrial electron transport, NADH to ubiquinone] GO:0007214 [gamma-aminobutyric acid signaling pathway] GO:0007399 [nervous system development] GO:0007406 [negative regulation of neuroblast proliferation] GO:0007411 [axon guidance] GO:0007412 [axon target recognition] GO:0007611 [learning or memory] GO:0007612 [learning] GO:0007623 [circadian rhythm] GO:0007631 [feeding behavior] GO:0008021 [synaptic vesicle] GO:0008038 [neuron recognition] GO:0008083 [growth factor activity] GO:0009416 [response to light stimulus] GO:0009642 [response to light intensity] GO:0009725 [response to hormone] GO:0010996 [response to auditory stimulus] GO:0014047 [glutamate secretion] GO:0014076 [response to fluoxetine] GO:0014823 [response to activity] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0016358 [dendrite development] GO:0019222 [regulation of metabolic process] GO:0021675 [nerve development] GO:0030061 [mitochondrial crista] GO:0030424 [axon] GO:0030425 [dendrite] GO:0030516 [regulation of axon extension] GO:0031667 [response to nutrient levels] GO:0032094 [response to food] GO:0032229 [negative regulation of synaptic transmission, GABAergic] GO:0033138 [positive regulation of peptidyl-serine phosphorylation] GO:0033189 [response to vitamin A] GO:0034612 [response to tumor necrosis factor] GO:0035864 [response to potassium ion] GO:0042490 [mechanoreceptor differentiation] GO:0042493 [response to drug] GO:0042596 [fear response] GO:0043025 [neuronal cell body] GO:0043066 [negative regulation of apoptotic process] GO:0043195 [terminal bouton] GO:0043204 [perikaryon] GO:0043523 [regulation of neuron apoptotic process] GO:0043524 [negative regulation of neuron apoptotic process] GO:0045666 [positive regulation of neuron differentiation] GO:0045843 [negative regulation of striated muscle tissue development] GO:0046668 [regulation of retinal cell programmed cell death] GO:0048167 [regulation of synaptic plasticity] GO:0048169 [regulation of long-term neuronal synaptic plasticity] GO:0048170 [positive regulation of long-term neuronal synaptic plasticity] GO:0048172 [regulation of short-term neuronal synaptic plasticity] GO:0048471 [perinuclear region of cytoplasm] GO:0048675 [axon extension] GO:0048839 [inner ear development] GO:0050890 [cognition] GO:0051602 [response to electrical stimulus] GO:0051965 [positive regulation of synapse assembly] GO:0055093 [response to hyperoxia] GO:0060079 [regulation of excitatory postsynaptic membrane potential] GO:0060548 [negative regulation of cell death] GO:0061193 [taste bud development] GO:0071356 [cellular response to tumor necrosis factor] GO:0071874 [cellular response to norepinephrine stimulus] GO:0072347 [response to anesthetic] GO:0097484 [dendrite extension] GO:1901215 [negative regulation of neuron death] GO:1902065 [response to L-glutamate] GO:1990089 [response to nerve growth factor] GO:1990090 [cellular response to nerve growth factor stimulus] GO:1990138 [neuron projection extension]	329	37.1	No	1
BDNF-009	ENSP00000435564 ENST00000530861	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-010	ENSP00000349084 ENST00000356660	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-011	ENSP00000400502 ENST00000418212	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-012	ENSP00000432376 ENST00000533246	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-013	ENSP00000379309 ENST00000395986	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:27%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q304R1 [Target identity:21%; Query identity:100%] Brain-derived neurotrophic factor preproprotein isoform 2 {ECO:0000313\|EMBL:ABB51155.1} Q969N8 [Target identity:17%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:11%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	262	29.8	No	0
BDNF-014	ENSP00000432727 ENST00000533131	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-015	ENSP00000389345 ENST00000439476	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-016	ENSP00000437138 ENST00000525528	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-018	ENSP00000320002 ENST00000314915	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:28%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:18%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q6T2C9 [Target identity:14%; Query identity:100%] Brain-derived neurotrophic factor isoform 1 {ECO:0000313\|EMBL:AAR14686.1} Q96TC2 [Target identity:11%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	255	28.9	Yes	0
BDNF-201	ENSP00000379304 ENST00000395980	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0
BDNF-202	ENSP00000389564 ENST00000420794	P23560 Show all » « Hide P23560 [Direct mapping] Brain-derived neurotrophic factor S5MI63 [Target identity:29%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:AGR50950.1} Q969N8 [Target identity:19%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55545.1} Q96TC2 [Target identity:12%; Query identity:100%] Brain-derived neurotrophic factor {ECO:0000313\|EMBL:BAB55546.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014)	Show » « Hide GO:0005102 [receptor binding] GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0007399 [nervous system development] GO:0008083 [growth factor activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly]	247	27.8	Yes	0

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.

Protein class

Predicted localization

Number of transcripts

RNA tissue category

Protein evidence

Protein localization

Data reliability description

Data reliability

RNA expression (FPKM)

Protein expression (score)

HPA dataset

RNA tissue category HPA

GTEx dataset

RNA tissue category GTEx