BDNF

GENE INFORMATION

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Gene name

BDNF

Synonyms

Description

Brain-derived neurotrophic factor (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]

Chromosome

11

Cytoband

p14.1

Chromosome location (bp)

27654893 - 27722058

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000176697 (version 78.38)

Entrez gene

627

UniProt

P23560 (UniProt - Evidence at protein level)

neXtProt

NX_P23560

Antibodypedia

BDNF antibodies
 

PROTEIN VIEW

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 « 
 
BDNF-001
 
BDNF-002
 
BDNF-003
 
BDNF-004
 
BDNF-007
 
BDNF-008
 
BDNF-009
 
BDNF-010
 
BDNF-011
 
BDNF-012
 
BDNF-013
 
BDNF-014
 
BDNF-015
 
BDNF-016
 
BDNF-018
 
BDNF-201
 
BDNF-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BDNF-001 ENSP00000432035
ENST00000525950
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-002 ENSP00000379305
ENST00000395981
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-003 ENSP00000379302
ENST00000395978
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-004 ENSP00000435805
ENST00000532997
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-007 ENSP00000379307
ENST00000395983
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-008 ENSP00000414303
ENST00000438929
P23560
Show all »
Show » Show » 329 37.1 No 1
BDNF-009 ENSP00000435564
ENST00000530861
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-010 ENSP00000349084
ENST00000356660
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-011 ENSP00000400502
ENST00000418212
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-012 ENSP00000432376
ENST00000533246
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-013 ENSP00000379309
ENST00000395986
P23560
Show all »
Show » Show » 262 29.8 No 0
BDNF-014 ENSP00000432727
ENST00000533131
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-015 ENSP00000389345
ENST00000439476
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-016 ENSP00000437138
ENST00000525528
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-018 ENSP00000320002
ENST00000314915
P23560
Show all »
Show » Show » 255 28.9 Yes 0
BDNF-201 ENSP00000379304
ENST00000395980
P23560
Show all »
Show » Show » 247 27.8 Yes 0
BDNF-202 ENSP00000389564
ENST00000420794
P23560
Show all »
Show » Show » 247 27.8 Yes 0