PIK3C2G

GENERAL INFORMATION

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Gene name

PIK3C2G

Gene description

Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (stomach)
GTEx:Tissue enhanced (skin, stomach)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (stomach)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (skin, stomach)

Organ

Expression



GENE INFORMATION

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Gene name

PIK3C2G

Synonyms

Description

Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Chromosome

12

Cytoband

p12.3

Chromosome location (bp)

18247614 - 18648416

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000139144 (version 78.38)

Entrez gene

5288

UniProt

O75747 (UniProt - Evidence at protein level)

neXtProt

NX_O75747

Antibodypedia

PIK3C2G antibodies


PROTEIN BROWSER

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ENST00000266497
 
ENST00000433979
 
ENST00000535651
 
ENST00000536967
 
ENST00000538779
 
ENST00000621090
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PIK3C2G-002 ENSP00000266497
ENST00000266497
O75747
Show all »
Show » Show » 1445 165.7 No 0
PIK3C2G-004 ENSP00000443850
ENST00000535651
F5H7Y7
Show all »
Show » Show » 583 67 No 0
PIK3C2G-005 ENSP00000479145
ENST00000536967
Show » 187 21.1 No 0
PIK3C2G-201 ENSP00000404845
ENST00000433979
O75747
Show all »
Show » Show » 1445 165.7 No 0
PIK3C2G-202 ENSP00000445381
ENST00000538779
F5H369
Show all »
Show » Show » 1486 170.7 No 0
PIK3C2G-203 ENSP00000481702
ENST00000621090
Show » Show » 1448 166 No 0