PIK3C2G

GENE INFORMATION

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Gene name

PIK3C2G

Synonyms

Description

Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Chromosome

12

Cytoband

p12.3

Chromosome location (bp)

18247614 - 18648416

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000139144 (version 78.38)

Entrez gene

5288

UniProt

O75747 (UniProt - Evidence at protein level)

neXtProt

NX_O75747

Antibodypedia

PIK3C2G antibodies
 

PROTEIN VIEW

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PIK3C2G-002
 
PIK3C2G-004
 
PIK3C2G-005
 
PIK3C2G-201
 
PIK3C2G-202
 
PIK3C2G-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PIK3C2G-002 ENSP00000266497
ENST00000266497
O75747
Show all »
Show » Show » 1445 165.7 No 0
PIK3C2G-004 ENSP00000443850
ENST00000535651
F5H7Y7
Show all »
Show » Show » 583 67 No 0
PIK3C2G-005 ENSP00000479145
ENST00000536967
Show » 187 21.1 No 0
PIK3C2G-201 ENSP00000404845
ENST00000433979
O75747
Show all »
Show » Show » 1445 165.7 No 0
PIK3C2G-202 ENSP00000445381
ENST00000538779
F5H369
Show all »
Show » Show » 1486 170.7 No 0
PIK3C2G-203 ENSP00000481702
ENST00000621090
Show » Show » 1448 166 No 0