HEY2

GENE INFORMATION

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Gene name

HEY2 (HGNC Symbol)

Synonyms

bHLHb32, HERP1, HESR2

Description

Hes-related family bHLH transcription factor with YRPW motif 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q22.31

Chromosome location (bp)

125747664 - 125761269

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135547 (version 78.38)

Entrez gene

23493

UniProt

Q9UBP5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UBP5

Antibodypedia

HEY2 antibodies
 

PROTEIN VIEW

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HEY2-001
 
HEY2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HEY2-001 ENSP00000357348
ENST00000368364
Q9UBP5
Show all »
Show » Show » 337 35.8 No 0
HEY2-002 ENSP00000357349
ENST00000368365
Q5TF93
Show all »
Show » Show » 291 30.8 No 0