DYNLRB1

GENERAL INFORMATION

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Gene name

DYNLRB1

Gene description

Dynein, light chain, roadblock-type 1

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
CAB009845
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

DYNLRB1 (HGNC Symbol)

Synonyms

DNCL2A, DNLC2A, ROBLD1

Description

Dynein, light chain, roadblock-type 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013]

Chromosome

20

Cytoband

q11.22

Chromosome location (bp)

34516409 - 34540958

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125971 (version 78.38)

Entrez gene

83658

UniProt

Q9NP97 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NP97

Antibodypedia

DYNLRB1 antibodies


PROTEIN BROWSER

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ENST00000300469
 
ENST00000357156
 
ENST00000374846
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DYNLRB1-002 ENSP00000349679
ENST00000357156
Q9NP97
Show all »
Show » Show » 96 10.9 No 0
DYNLRB1-003 ENSP00000300469
ENST00000300469
Q9NP97
Show all »
Show » Show » 47 5.1 No 0
DYNLRB1-004 ENSP00000363979
ENST00000374846
B1AKR6
Show all »
Show » 148 16.3 No 0