DYNLRB1

GENE INFORMATION

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Gene name

DYNLRB1 (HGNC Symbol)

Synonyms

DNCL2A, DNLC2A, ROBLD1

Description

Dynein, light chain, roadblock-type 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013]

Chromosome

20

Cytoband

q11.22

Chromosome location (bp)

34516409 - 34540958

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125971 (version 78.38)

Entrez gene

83658

UniProt

Q9NP97 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NP97

Antibodypedia

DYNLRB1 antibodies
 

PROTEIN VIEW

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DYNLRB1-002
 
DYNLRB1-003
 
DYNLRB1-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DYNLRB1-002 ENSP00000349679
ENST00000357156
Q9NP97
Show all »
Show » Show » 96 10.9 No 0
DYNLRB1-003 ENSP00000300469
ENST00000300469
Q9NP97
Show all »
Show » Show » 47 5.1 No 0
DYNLRB1-004 ENSP00000363979
ENST00000374846
B1AKR6
Show all »
Show » 148 16.3 No 0