PREX1

GENE INFORMATION

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Gene name

PREX1 (HGNC Symbol)

Synonyms

KIAA1415, P-REX1

Description

Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q13.13

Chromosome location (bp)

48624252 - 48827883

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124126 (version 78.38)

Entrez gene

57580

UniProt

Q8TCU6 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TCU6

Antibodypedia

PREX1 antibodies
 

PROTEIN VIEW

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PREX1-001
 
PREX1-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PREX1-001 ENSP00000361009
ENST00000371941
Q8TCU6
Show all »
Show » Show » 1659 186.2 No 0
PREX1-004 ENSP00000481444
ENST00000620554
Show » 12 1.1 No 0