NDUFB3

GENE INFORMATION

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Gene name

NDUFB3 (HGNC Symbol)

Synonyms

B12

Description

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa (HGNC Symbol)

Entrez gene summary

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene. [provided by RefSeq, Mar 2012]

Chromosome

2

Cytoband

q33.1

Chromosome location (bp)

201071433 - 201085750

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000119013 (version 78.38)

Entrez gene

4709

UniProt

O43676 (UniProt - Evidence at protein level)

neXtProt

NX_O43676

Antibodypedia

NDUFB3 antibodies
 

PROTEIN VIEW

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NDUFB3-001
 
NDUFB3-002
 
NDUFB3-003
 
NDUFB3-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NDUFB3-001 ENSP00000237889
ENST00000237889
O43676
Show all »
Show » Show » 98 11.4 No 1
NDUFB3-002 ENSP00000401834
ENST00000450023
C9JKQ2
Show all »
Show » Show » 65 7.6 No 0
NDUFB3-003 ENSP00000410600
ENST00000433898
O43676
Show all »
Show » Show » 98 11.4 No 1
NDUFB3-004 ENSP00000407336
ENST00000454214
O43676
Show all »
Show » Show » 98 11.4 No 1