TNFAIP3

GENE INFORMATION

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Gene name

TNFAIP3 (HGNC Symbol)

Synonyms

A20, OTUD7C

Description

Tumor necrosis factor, alpha-induced protein 3 (HGNC Symbol)

Entrez gene summary

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]

Chromosome

6

Cytoband

q23.3

Chromosome location (bp)

137867188 - 137883312

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000118503 (version 78.38)

Entrez gene

7128

UniProt

P21580 (UniProt - Evidence at protein level)

neXtProt

NX_P21580

Antibodypedia

TNFAIP3 antibodies
 

PROTEIN VIEW

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TNFAIP3-001
 
TNFAIP3-002
 
TNFAIP3-003
 
TNFAIP3-004
 
TNFAIP3-201
 
TNFAIP3-202
 
TNFAIP3-203
 
TNFAIP3-204
 
TNFAIP3-205
 
TNFAIP3-206
 
TNFAIP3-207
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TNFAIP3-001 ENSP00000237289
ENST00000237289
P21580
Show all »
Show » Show » 790 89.6 No 0
TNFAIP3-002 ENSP00000393577
ENST00000421450
Q5VXR0
Show all »
Show » 26 3 No 0
TNFAIP3-003 ENSP00000401562
ENST00000420009
Q5VXQ8
Show all »
Show » 162 19.2 No 0
TNFAIP3-004 ENSP00000409845
ENST00000433680
Q5VXQ9
Show all »
Show » 98 11.8 No 0
TNFAIP3-201 ENSP00000481570
ENST00000612899
P21580
Show all »
Show » Show » 790 89.6 No 0
TNFAIP3-202 ENSP00000481122
ENST00000614035
D3TTY9
Show all »
Show » Show » 470 54.3 No 0
TNFAIP3-203 ENSP00000481199
ENST00000614451
D3TTY7
Show all »
Show » 152 18 No 0
TNFAIP3-204 ENSP00000479556
ENST00000615468
D3TTZ6
Show all »
Show » 214 25.5 No 0
TNFAIP3-205 ENSP00000478438
ENST00000619035
D3TTZ2
Show all »
Show » Show » 749 84.9 No 0
TNFAIP3-206 ENSP00000481454
ENST00000620204
D3TTY5
Show all »
Show » Show » 669 76.2 No 0
TNFAIP3-207 ENSP00000484332
ENST00000621150
D3TTY6
Show all »
Show » Show » 531 61.1 No 0