PDE10A

GENE INFORMATION

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Gene name

PDE10A

Synonyms

Description

Phosphodiesterase 10A (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]

Chromosome

6

Cytoband

q27

Chromosome location (bp)

165327287 - 165986603

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112541 (version 78.38)

Entrez gene

10846

UniProt

Q9Y233 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y233

Antibodypedia

PDE10A antibodies
 

PROTEIN VIEW

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PDE10A-001
 
PDE10A-002
 
PDE10A-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PDE10A-001 ENSP00000355847
ENST00000366882
Q9Y233
Show all »
Show » Show » 779 88.4 No 0
PDE10A-002 ENSP00000438284
ENST00000539869
Q9Y233
Show all »
Show » Show » 789 89.4 No 0
PDE10A-201 ENSP00000478556
ENST00000616273
Show » 183 19.3 No 0