EIF3D

GENERAL INFORMATION

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Gene name

EIF3D

Gene description

Eukaryotic translation initiation factor 3, subunit D

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA063330 , HPA066216
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

EIF3D (HGNC Symbol)

Synonyms

eIF3-p66, eIF3-zeta, eIF3d, EIF3S7

Description

Eukaryotic translation initiation factor 3, subunit D (HGNC Symbol)

Entrez gene summary

Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]

Chromosome

22

Cytoband

q12.3

Chromosome location (bp)

36510850 - 36529436

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100353 (version 78.38)

Entrez gene

8664

UniProt

O15371 (UniProt - Evidence at protein level)

neXtProt

NX_O15371

Antibodypedia

EIF3D antibodies


PROTEIN BROWSER

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ENST00000216190
 
ENST00000402116
 
ENST00000405442
 
ENST00000432675
 
ENST00000455547
 
ENST00000457241
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EIF3D-001 ENSP00000216190
ENST00000216190
O15371
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Show » Show » 548 64 No 0
EIF3D-002 ENSP00000385812
ENST00000405442
O15371
Show all »
Show » Show » 548 64 No 0
EIF3D-003 ENSP00000402192
ENST00000432675
B0QYA7
Show all »
Show » Show » 186 22.2 No 0
EIF3D-005 ENSP00000390438
ENST00000455547
B0QYA5
Show all »
Show » Show » 269 31.7 No 0
EIF3D-006 ENSP00000403584
ENST00000457241
B0QYA6
Show all »
Show » Show » 173 20.7 No 0
EIF3D-007 ENSP00000385212
ENST00000402116
B0QYA8
Show all »
Show » Show » 123 14.5 No 0