EIF3D

GENE INFORMATION

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Gene name

EIF3D (HGNC Symbol)

Synonyms

eIF3-p66, eIF3-zeta, eIF3d, EIF3S7

Description

Eukaryotic translation initiation factor 3, subunit D (HGNC Symbol)

Entrez gene summary

Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]

Chromosome

22

Cytoband

q12.3

Chromosome location (bp)

36510850 - 36529436

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100353 (version 78.38)

Entrez gene

8664

UniProt

O15371 (UniProt - Evidence at protein level)

neXtProt

NX_O15371

Antibodypedia

EIF3D antibodies
 

PROTEIN VIEW

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EIF3D-001
 
EIF3D-002
 
EIF3D-003
 
EIF3D-005
 
EIF3D-006
 
EIF3D-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EIF3D-001 ENSP00000216190
ENST00000216190
O15371
Show all »
Show » Show » 548 64 No 0
EIF3D-002 ENSP00000385812
ENST00000405442
O15371
Show all »
Show » Show » 548 64 No 0
EIF3D-003 ENSP00000402192
ENST00000432675
B0QYA7
Show all »
Show » Show » 186 22.2 No 0
EIF3D-005 ENSP00000390438
ENST00000455547
B0QYA5
Show all »
Show » Show » 269 31.7 No 0
EIF3D-006 ENSP00000403584
ENST00000457241
B0QYA6
Show all »
Show » Show » 173 20.7 No 0
EIF3D-007 ENSP00000385212
ENST00000402116
B0QYA8
Show all »
Show » Show » 123 14.5 No 0