MTMR3

GENE INFORMATION

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Gene name

MTMR3 (HGNC Symbol)

Synonyms

FYVE-DSP1, KIAA0371, ZFYVE10

Description

Myotubularin related protein 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

22

Cytoband

q12.2

Chromosome location (bp)

29883155 - 30030866

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100330 (version 78.38)

Entrez gene

8897

UniProt

Q13615 (UniProt - Evidence at protein level)

neXtProt

NX_Q13615

Antibodypedia

MTMR3 antibodies
 

PROTEIN VIEW

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MTMR3-001
 
MTMR3-002
 
MTMR3-003
 
MTMR3-004
 
MTMR3-006
 
MTMR3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MTMR3-001 ENSP00000384651
ENST00000401950
Q13615
Show all »
Show » Show » 1198 133.6 No 0
MTMR3-002 ENSP00000307271
ENST00000351488
Q13615
Show all »
Show » Show » 1161 129.4 No 0
MTMR3-003 ENSP00000384077
ENST00000406629
Q13615
Show all »
Show » Show » 1170 130.6 No 0
MTMR3-004 ENSP00000318070
ENST00000323630
G5E953
Show all »
Show » Show » 1062 117.6 No 0
MTMR3-006 ENSP00000409063
ENST00000445401
C9JLU3
Show all »
Show » 139 16.4 No 0
MTMR3-201 ENSP00000331649
ENST00000333027
Q13615
Show all »
Show » Show » 1170 130.6 No 0