PES1

GENERAL INFORMATION

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Gene name

PES1

Gene description

Pescadillo ribosomal biogenesis factor 1

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Nucleolar expression in several tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
HPA062439
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PES1 (HGNC Symbol)

Synonyms

PES

Description

Pescadillo ribosomal biogenesis factor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9. [provided by RefSeq, Aug 2011]

Chromosome

22

Cytoband

q12.2

Chromosome location (bp)

30576625 - 30607083

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100029 (version 78.38)

Entrez gene

23481

UniProt

O00541 (UniProt - Evidence at protein level)

neXtProt

NX_O00541

Antibodypedia

PES1 antibodies


PROTEIN BROWSER

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ENST00000335214
 
ENST00000354694
 
ENST00000402281
 
ENST00000402284
 
ENST00000405677
 
ENST00000441668
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PES1-001 ENSP00000346725
ENST00000354694
O00541
Show all »
Show » Show » 588 68 No 0
PES1-002 ENSP00000385654
ENST00000405677
B3KXD6
Show all »
Show » Show » 449 51.5 No 0
PES1-003 ENSP00000384366
ENST00000402281
B3KXD6
Show all »
Show » Show » 449 51.5 No 0
PES1-004 ENSP00000384252
ENST00000402284
B5MCF9
Show all »
Show » Show » 571 66.1 No 0
PES1-005 ENSP00000334612
ENST00000335214
O00541
Show all »
Show » Show » 583 67.5 No 0
PES1-013 ENSP00000404234
ENST00000441668
Show » 194 22.3 No 0