PES1

GENE INFORMATION

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Gene name

PES1 (HGNC Symbol)

Synonyms

PES

Description

Pescadillo ribosomal biogenesis factor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9. [provided by RefSeq, Aug 2011]

Chromosome

22

Cytoband

q12.2

Chromosome location (bp)

30576625 - 30607083

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100029 (version 78.38)

Entrez gene

23481

UniProt

O00541 (UniProt - Evidence at protein level)

neXtProt

NX_O00541

Antibodypedia

PES1 antibodies
 

PROTEIN VIEW

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PES1-001
 
PES1-002
 
PES1-003
 
PES1-004
 
PES1-005
 
PES1-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PES1-001 ENSP00000346725
ENST00000354694
O00541
Show all »
Show » Show » 588 68 No 0
PES1-002 ENSP00000385654
ENST00000405677
B3KXD6
Show all »
Show » Show » 449 51.5 No 0
PES1-003 ENSP00000384366
ENST00000402281
B3KXD6
Show all »
Show » Show » 449 51.5 No 0
PES1-004 ENSP00000384252
ENST00000402284
B5MCF9
Show all »
Show » Show » 571 66.1 No 0
PES1-005 ENSP00000334612
ENST00000335214
O00541
Show all »
Show » Show » 583 67.5 No 0
PES1-013 ENSP00000404234
ENST00000441668
Show » 194 22.3 No 0