DNM1

GENE INFORMATION

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Gene name

DNM1 (HGNC Symbol)

Synonyms

DNM

Description

Dynamin 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q34.11

Chromosome location (bp)

128203379 - 128255248

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106976 (version 78.38)

Entrez gene

1759

UniProt

Q05193 (UniProt - Evidence at protein level)

neXtProt

NX_Q05193

Antibodypedia

DNM1 antibodies
 

PROTEIN VIEW

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DNM1-001
 
DNM1-002
 
DNM1-007
 
DNM1-009
 
DNM1-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DNM1-001 ENSP00000362014
ENST00000372923
Q05193
Show all »
Show » Show » 864 97.4 No 0
DNM1-002 ENSP00000377219
ENST00000393594
Q05193
Show all »
Show » Show » 851 95.9 No 0
DNM1-007 ENSP00000419225
ENST00000475805
Q05193
Show all »
Show » Show » 851 95.9 No 0
DNM1-009 ENSP00000345680
ENST00000341179
Q05193
Show all »
Show » Show » 851 96 No 0
DNM1-010 ENSP00000420045
ENST00000486160
Q05193
Show all »
Show » Show » 864 97.3 No 0