HIST1H4A

GENE INFORMATION

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Gene name

HIST1H4A (HGNC Symbol)

Synonyms

H4FA

Description

Histone cluster 1, H4a (HGNC Symbol)

Entrez gene summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p22.2

Chromosome location (bp)

26021679 - 26021990

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000278637 (version 78.38)

Entrez gene

8359

UniProt

P62805 (UniProt - Evidence at protein level)

neXtProt

NX_P62805

Antibodypedia

HIST1H4A antibodies
 

PROTEIN VIEW

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HIST1H4A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HIST1H4A-001 ENSP00000479106
ENST00000617569
P62805
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