HIST1H4K

GENERAL INFORMATION

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Gene name

HIST1H4K

Gene description

Histone cluster 1, H4k

Protein class

Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed

Protein evidence

Evidence at protein level

Protein localization

General nuclear expression, most abundant in proliferating cells.

ANTIBODY RELIABILITY

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Data reliability
description

Caution, targets protein from more than one gene. Correlation with RNA expression data cannot be evaluated due to technical limitations (poly-A tail missing).

Data reliability

Supportive based on 1 antibody.
HPA042201
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

HIST1H4K (HGNC Symbol)

Synonyms

dJ160A22.1, H4/d, H4F2iii, H4FD

Description

Histone cluster 1, H4k (HGNC Symbol)

Entrez gene summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p22.1

Chromosome location (bp)

27831216 - 27831527

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000273542 (version 78.38)

Entrez gene

8362

UniProt

P62805 (UniProt - Evidence at protein level)

neXtProt

NX_P62805

Antibodypedia

HIST1H4K antibodies


PROTEIN BROWSER

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ENST00000611927
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HIST1H4K-001 ENSP00000479794
ENST00000611927
P62805
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