HIST2H4A

GENE INFORMATION

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Gene name

HIST2H4A (HGNC Symbol)

Synonyms

H4/n, H4F2, H4FN, HIST2H4

Description

Histone cluster 2, H4a (HGNC Symbol)

Entrez gene summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q21.2

Chromosome location (bp)

149832659 - 149839767

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000270882 (version 78.38)

Entrez gene

8370

UniProt

neXtProt

Antibodypedia

HIST2H4A antibodies
 

PROTEIN VIEW

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HIST2H4A-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HIST2H4A-004 ENSP00000462667
ENST00000578186
B2R4R0
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