EGLN2

GENE INFORMATION

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Gene name

EGLN2 (HGNC Symbol)

Synonyms

HIFPH1, PHD1

Description

Egl-9 family hypoxia-inducible factor 2 (HGNC Symbol)

Entrez gene summary

The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]

Chromosome

19

Cytoband

q13.2

Chromosome location (bp)

40798996 - 40808433

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000269858 (version 78.38)

Entrez gene

112398

UniProt

Q96KS0 (UniProt - Evidence at protein level)

neXtProt

NX_Q96KS0

Antibodypedia

EGLN2 antibodies
 

PROTEIN VIEW

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 « 
 
EGLN2-001
 
EGLN2-002
 
EGLN2-003
 
EGLN2-006
 
EGLN2-007
 
EGLN2-008
 
EGLN2-009
 
EGLN2-010
 
EGLN2-011
 
EGLN2-012
 
EGLN2-013
 
EGLN2-014
 
EGLN2-015
 
EGLN2-018
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EGLN2-001 ENSP00000307080
ENST00000303961
Q96KS0
Show all »
Show » Show » 407 43.7 No 0
EGLN2-002 ENSP00000385253
ENST00000406058
Q96KS0
Show all »
Show » Show » 407 43.7 No 0
EGLN2-003 ENSP00000469686
ENST00000593726
Q96KS0
Show all »
Show » Show » 407 43.7 No 0
EGLN2-006 ENSP00000471568
ENST00000598654
M0R110
Show all »
Show » Show » 101 10.2 No 0
EGLN2-007 ENSP00000471546
ENST00000593972
M0R0Z6
Show all »
Show » Show » 139 14.4 No 0
EGLN2-008 ENSP00000472870
ENST00000596517
M0R2X9
Show all »
Show » 67 6.9 No 0
EGLN2-009 ENSP00000469323
ENST00000601733
M0QXR0
Show all »
Show » Show » 94 9.6 No 0
EGLN2-010 ENSP00000470968
ENST00000594380
M0R035
Show all »
Show » Show » 88 8.9 No 0
EGLN2-011 ENSP00000472146
ENST00000593397
M0R1W4
Show all »
Show » Show » 72 7.4 No 0
EGLN2-012 ENSP00000472991
ENST00000597746
M0R350
Show all »
Show » Show » 128 14.2 No 0
EGLN2-013 ENSP00000471944
ENST00000595621
Show » 96 10.5 No 0
EGLN2-014 ENSP00000471740
ENST00000595051
M0R1A3
Show all »
Show » 51 5.7 No 0
EGLN2-015 ENSP00000472414
ENST00000594140
Q96KS0
Show all »
Show » Show » 125 14.1 No 0
EGLN2-018 ENSP00000469272
ENST00000593525
M0QXM8
Show all »
Show » Show » 77 7.9 No 0