TRPV1

GENE INFORMATION

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Gene name

TRPV1 (HGNC Symbol)

Synonyms

VR1

Description

Transient receptor potential cation channel, subfamily V, member 1 (HGNC Symbol)

Entrez gene summary

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

p13.2

Chromosome location (bp)

3565444 - 3636249

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000262304 (version 78.38)

Entrez gene

7442

UniProt

Q8NER1 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NER1

Antibodypedia

TRPV1 antibodies
 

PROTEIN VIEW

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TRPV1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRPV1-002 ENSP00000459962
ENST00000572705
Q8NER1
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