GAN

GENE INFORMATION

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Gene name

GAN (HGNC Symbol)

Synonyms

GAN1, KLHL16

Description

Gigaxonin (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN). [provided by RefSeq, Oct 2008]

Chromosome

16

Cytoband

q23.2

Chromosome location (bp)

81314952 - 81390884

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000261609 (version 78.38)

Entrez gene

8139

UniProt

Q9H2C0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H2C0

Antibodypedia

GAN antibodies
 

PROTEIN VIEW

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GAN-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GAN-001 ENSP00000476795
ENST00000568107
Q9H2C0
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