UGT1A9

GENE INFORMATION

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Gene name

UGT1A9 (HGNC Symbol)

Synonyms

HLUGP4, LUGP4, UGT1AI

Description

UDP glucuronosyltransferase 1 family, polypeptide A9 (HGNC Symbol)

Entrez gene summary

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q37.1

Chromosome location (bp)

233671853 - 233773300

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000241119 (version 78.38)

Entrez gene

54600

UniProt

O60656 (UniProt - Evidence at protein level)

neXtProt

NX_O60656

Antibodypedia

UGT1A9 antibodies
 

PROTEIN VIEW

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UGT1A9-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UGT1A9-001 ENSP00000346768
ENST00000354728
O60656
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