LILRA2

GENE INFORMATION

? »

Gene name

LILRA2 (HGNC Symbol)

Synonyms

CD85h, ILT1, LIR-7, LIR7

Description

Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of immunoreceptors that are expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and there is a pseudogene for this gene on chromosome 3. [provided by RefSeq, Mar 2014]

Chromosome

19

Cytoband

q13.42

Chromosome location (bp)

54572920 - 54587560

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000239998 (version 78.38)

Entrez gene

11027

UniProt

Q8N149 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N149

Antibodypedia

LILRA2 antibodies
 

PROTEIN VIEW

? »
 
 
 
LILRA2-001
 
LILRA2-002
 
LILRA2-003
 
LILRA2-006
 
LILRA2-007
 
LILRA2-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LILRA2-001 ENSP00000251377
ENST00000251377
Q8N149
Show all »
Show » Show » 483 53 Yes 1
LILRA2-002 ENSP00000375617
ENST00000391737
Show » Show » 454 50 Yes 1
LILRA2-003 ENSP00000251376
ENST00000251376
Q8N149
Show all »
Show » Show » 466 51.2 Yes 1
LILRA2-006 ENSP00000388131
ENST00000439534
Show » Show » 327 36.1 Yes 0
LILRA2-007 ENSP00000477566
ENST00000472992
Show » 85 8.6 No 0
LILRA2-201 ENSP00000375618
ENST00000391738
Q8N149
Show all »
Show » Show » 483 53 Yes 1