HLA-DQA2

GENE INFORMATION

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Gene name

HLA-DQA2 (HGNC Symbol)

Synonyms

HLA-DXA

Description

Major histocompatibility complex, class II, DQ alpha 2 (HGNC Symbol)

Entrez gene summary

This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010]

Chromosome

6

Cytoband

p21.32

Chromosome location (bp)

32741342 - 32747215

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000237541 (version 78.38)

Entrez gene

3118

UniProt

P01906 (UniProt - Evidence at protein level)

neXtProt

NX_P01906

Antibodypedia

HLA-DQA2 antibodies
 

PROTEIN VIEW

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HLA-DQA2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HLA-DQA2-001 ENSP00000364076
ENST00000374940
P01906
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