VPS16

GENE INFORMATION

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Gene name

VPS16

Synonyms

Description

Vacuolar protein sorting 16 homolog (S. cerevisiae) (HGNC Symbol)

Entrez gene summary

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

2840703 - 2866732

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000215305 (version 78.38)

Entrez gene

64601

UniProt

Q9H269 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H269

Antibodypedia

VPS16 antibodies
 

PROTEIN VIEW

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VPS16-001
 
VPS16-003
 
VPS16-004
 
VPS16-005
 
VPS16-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VPS16-001 ENSP00000369810
ENST00000380445
Q9H269
Show all »
Show » Show » 839 94.7 No 0
VPS16-003 ENSP00000369836
ENST00000380469
Q9H269
Show all »
Show » Show » 695 78.3 No 0
VPS16-004 ENSP00000409840
ENST00000417508
Q5JUB0
Show all »
Show » Show » 227 25.1 No 0
VPS16-005 ENSP00000417031
ENST00000453689
Q5JUA9
Show all »
Show » Show » 274 30.4 No 0
VPS16-006 ENSP00000369808
ENST00000380443
Q5JUA8
Show all »
Show » Show » 525 59.3 No 0