PEX26

GENE INFORMATION

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Gene name

PEX26 (HGNC Symbol)

Synonyms

FLJ20695

Description

Peroxisomal biogenesis factor 26 (HGNC Symbol)

Entrez gene summary

This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Dec 2010]

Chromosome

22

Cytoband

q11.21

Chromosome location (bp)

18077920 - 18131138

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000215193 (version 78.38)

Entrez gene

55670

UniProt

Q7Z412 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z412

Antibodypedia

PEX26 antibodies
 

PROTEIN VIEW

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PEX26-001
 
PEX26-002
 
PEX26-003
 
PEX26-201
 
PEX26-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PEX26-001 ENSP00000331106
ENST00000329627
Q7Z412
Show all »
Show » Show » 305 33.9 No 1
PEX26-002 ENSP00000382648
ENST00000399744
Q7Z412
Show all »
Show » Show » 305 33.9 No 1
PEX26-003 ENSP00000412441
ENST00000428061
Q7Z412
Show all »
Show » Show » 256 28.4 No 0
PEX26-201 ENSP00000482091
ENST00000610387
Q7Z412
Show all »
Show » Show » 256 28.4 No 0
PEX26-202 ENSP00000483492
ENST00000618979
Show » Show » 365 39.9 No 1