MXD3

GENE INFORMATION

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Gene name

MXD3 (HGNC Symbol)

Synonyms

bHLHc13, MAD3

Description

MAX dimerization protein 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]

Chromosome

5

Cytoband

q35.3

Chromosome location (bp)

177301461 - 177312757

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000213347 (version 78.38)

Entrez gene

83463

UniProt

Q9BW11 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9BW11

Antibodypedia

MXD3 antibodies
 

PROTEIN VIEW

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MXD3-001
 
MXD3-002
 
MXD3-003
 
MXD3-006
 
MXD3-008
 
MXD3-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MXD3-001 ENSP00000401867
ENST00000439742
Q9BW11
Show all »
Show » Show » 206 23.5 No 0
MXD3-002 ENSP00000389716
ENST00000423571
B4E0J1
Show all »
Show » Show » 388 42.8 No 0
MXD3-003 ENSP00000416921
ENST00000427908
Q9BW11
Show all »
Show » Show » 193 22.1 No 0
MXD3-006 ENSP00000425029
ENST00000502529
D6RED4
Show all »
Show » Show » 124 14.5 No 0
MXD3-008 ENSP00000427104
ENST00000513169
D6RD21
Show all »
Show » Show » 75 8.7 No 0
MXD3-009 ENSP00000421463
ENST00000513063
Q9BW11
Show all »
Show » Show » 206 23.5 No 0