PBX2

GENE INFORMATION

? »

Gene name

PBX2 (HGNC Symbol)

Synonyms

G17, HOX12, PBX2MHC

Description

Pre-B-cell leukemia homeobox 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p21.32

Chromosome location (bp)

32184741 - 32190186

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204304 (version 78.38)

Entrez gene

5089

UniProt

P40425 (UniProt - Evidence at protein level)

neXtProt

NX_P40425

Antibodypedia

PBX2 antibodies
 

PROTEIN VIEW

? »
 
 
 
PBX2-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PBX2-001 ENSP00000364190
ENST00000375050
P40425
Show all »
Show » Show » 430 45.9 No 0