DCLRE1A

GENERAL INFORMATION

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Gene name

DCLRE1A

Gene description

DNA cross-link repair 1A

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Nuclear expression in several tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA036907
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

DCLRE1A (HGNC Symbol)

Synonyms

hSNM1, KIAA0086, PSO2, SNM1

Description

DNA cross-link repair 1A (HGNC Symbol)

Entrez gene summary

This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Chromosome

10

Cytoband

q25.3

Chromosome location (bp)

113834725 - 113854383

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198924 (version 78.38)

Entrez gene

9937

UniProt

Q6PJP8 (UniProt - Evidence at protein level)

neXtProt

NX_Q6PJP8

Antibodypedia

DCLRE1A antibodies


PROTEIN BROWSER

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ENST00000361384
 
ENST00000369305
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DCLRE1A-001 ENSP00000358311
ENST00000369305
Q6PJP8
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Show » Show » 1040 116.4 No 0
DCLRE1A-002 ENSP00000355185
ENST00000361384
Q6PJP8
Show all »
Show » Show » 1040 116.4 No 0