SREBF2

GENE INFORMATION

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Gene name

SREBF2 (HGNC Symbol)

Synonyms

bHLHd2, SREBP2

Description

Sterol regulatory element binding transcription factor 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Chromosome

22

Cytoband

q13.2

Chromosome location (bp)

41833079 - 41907308

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198911 (version 78.38)

Entrez gene

6721

UniProt

Q12772 (UniProt - Evidence at protein level)

neXtProt

NX_Q12772

Antibodypedia

SREBF2 antibodies
 

PROTEIN VIEW

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SREBF2-001
 
SREBF2-005
 
SREBF2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SREBF2-001 ENSP00000354476
ENST00000361204
Q12772
Show all »
Show » Show » 1141 123.7 No 2
SREBF2-005 ENSP00000412287
ENST00000435061
Show » 257 28 No 0
SREBF2-201 ENSP00000484441
ENST00000612482
Show » Show » 654 70.3 No 2