CYP2A7

GENE INFORMATION

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Gene name

CYP2A7 (HGNC Symbol)

Synonyms

CYP2A

Description

Cytochrome P450, family 2, subfamily A, polypeptide 7 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.2

Chromosome location (bp)

40875439 - 40882752

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198077 (version 78.38)

Entrez gene

1549

UniProt

P20853 (UniProt - Evidence at protein level)

neXtProt

NX_P20853

Antibodypedia

CYP2A7 antibodies
 

PROTEIN VIEW

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CYP2A7-001
 
CYP2A7-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP2A7-001 ENSP00000301146
ENST00000301146
P20853
Show all »
Show » Show » 494 56.4 Yes 0
CYP2A7-201 ENSP00000291764
ENST00000291764
F8W816
Show all »
Show » Show » 443 50.7 Yes 0