CYP2F1

GENE INFORMATION

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Gene name

CYP2F1 (HGNC Symbol)

Synonyms

CYP2F

Description

Cytochrome P450, family 2, subfamily F, polypeptide 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.2

Chromosome location (bp)

41114432 - 41128366

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000197446 (version 78.38)

Entrez gene

1572

UniProt

P24903 (UniProt - Evidence at protein level)

neXtProt

NX_P24903

Antibodypedia

CYP2F1 antibodies
 

PROTEIN VIEW

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CYP2F1-001
 
CYP2F1-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP2F1-001 ENSP00000333534
ENST00000331105
P24903
Show all »
Show » Show » 491 55.5 Yes 0
CYP2F1-007 ENSP00000443424
ENST00000439903
Show » Show » 81 9.1 No 0