ENTPD4

GENE INFORMATION

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Gene name

ENTPD4 (HGNC Symbol)

Synonyms

KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase

Description

Ectonucleoside triphosphate diphosphohydrolase 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq, Sep 2011]

Chromosome

8

Cytoband

p21.3

Chromosome location (bp)

23385783 - 23457695

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000197217 (version 78.38)

Entrez gene

9583

UniProt

Q9Y227 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y227

Antibodypedia

ENTPD4 antibodies
 

PROTEIN VIEW

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ENTPD4-001
 
ENTPD4-002
 
ENTPD4-004
 
ENTPD4-005
 
ENTPD4-006
 
ENTPD4-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ENTPD4-001 ENSP00000351520
ENST00000358689
Q9Y227
Show all »
Show » Show » 616 70.3 No 2
ENTPD4-002 ENSP00000408573
ENST00000417069
Q9Y227
Show all »
Show » Show » 608 69.4 No 2
ENTPD4-004 ENSP00000348536
ENST00000356206
Q8NE73
Show all »
Show » Show » 571 64.9 No 1
ENTPD4-005 ENSP00000429455
ENST00000518718
E5RIB2
Show all »
Show » Show » 127 14.4 No 0
ENTPD4-006 ENSP00000427724
ENST00000519839
Show » Show » 117 13.5 No 0
ENTPD4-012 ENSP00000430579
ENST00000518471
H0YBY8
Show all »
Show » Show » 214 24.7 No 0