PDLIM7

GENE INFORMATION

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Gene name

PDLIM7 (HGNC Symbol)

Synonyms

ENIGMA

Description

PDZ and LIM domain 7 (enigma) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q35.3

Chromosome location (bp)

177483394 - 177497606

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000196923 (version 78.38)

Entrez gene

9260

UniProt

Q9NR12 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NR12

Antibodypedia

PDLIM7 antibodies
 

PROTEIN VIEW

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PDLIM7-001
 
PDLIM7-003
 
PDLIM7-004
 
PDLIM7-007
 
PDLIM7-009
 
PDLIM7-010
 
PDLIM7-012
 
PDLIM7-015
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PDLIM7-001 ENSP00000348099
ENST00000355841
Q9NR12
Show all »
Show » Show » 457 49.8 No 0
PDLIM7-003 ENSP00000352964
ENST00000359895
Q9NR12
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Show » Show » 423 46.5 No 0
PDLIM7-004 ENSP00000347776
ENST00000355572
Q9NR12
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Show » Show » 222 24.4 No 0
PDLIM7-007 ENSP00000377182
ENST00000393551
Q9NR12
Show all »
Show » Show » 287 30.4 No 0
PDLIM7-009 ENSP00000424850
ENST00000506161
D6RF83
Show all »
Show » Show » 173 18.5 No 0
PDLIM7-010 ENSP00000421664
ENST00000506537
D6RAN1
Show all »
Show » Show » 90 9.5 No 0
PDLIM7-012 ENSP00000377177
ENST00000393546
H7BYK4
Show all »
Show » Show » 195 20.6 No 0
PDLIM7-015 ENSP00000426213
ENST00000505074
D6RH06
Show all »
Show » Show » 287 30.6 No 0