PTPRT

GENE INFORMATION

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Gene name

PTPRT (HGNC Symbol)

Synonyms

KIAA0283, RPTPrho

Description

Protein tyrosine phosphatase, receptor type, T (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

Chromosome location (bp)

42072752 - 43189970

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000196090 (version 78.38)

Entrez gene

11122

UniProt

O14522 (UniProt - Evidence at protein level)

neXtProt

NX_O14522

Antibodypedia

PTPRT antibodies
 

PROTEIN VIEW

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PTPRT-001
 
PTPRT-002
 
PTPRT-004
 
PTPRT-005
 
PTPRT-006
 
PTPRT-007
 
PTPRT-009
 
PTPRT-201
 
PTPRT-202
 
PTPRT-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PTPRT-001 ENSP00000362286
ENST00000373190
B1AJR6
Show all »
Show » Show » 1440 162 Yes 1
PTPRT-002 ENSP00000362283
ENST00000373187
O14522
Show all »
Show » Show » 1441 162.1 Yes 1
PTPRT-004 ENSP00000348408
ENST00000356100
B1AJR8
Show all »
Show » Show » 1450 162.7 Yes 1
PTPRT-005 ENSP00000362294
ENST00000373198
A0A075B6H0
Show all »
Show » Show » 1460 164 Yes 1
PTPRT-006 ENSP00000362280
ENST00000373184
B1AJR9
Show all »
Show » Show » 1451 162.8 Yes 1
PTPRT-007 ENSP00000362297
ENST00000373201
B1AJS0
Show all »
Show » Show » 1431 160.9 Yes 1
PTPRT-009 ENSP00000362289
ENST00000373193
O14522
Show all »
Show » Show » 1463 164.3 Yes 1
PTPRT-201 ENSP00000481466
ENST00000612229
Show » Show » 1059 120.3 No 1
PTPRT-202 ENSP00000484524
ENST00000618610
Show » Show » 1076 121.8 No 1
PTPRT-203 ENSP00000480136
ENST00000620410
Show » Show » 313 34.6 No 0