FANCM

GENE INFORMATION

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Gene name

FANCM (HGNC Symbol)

Synonyms

FAAP250, KIAA1596

Description

Fanconi anemia, complementation group M (HGNC Symbol)

Entrez gene summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q21.2

Chromosome location (bp)

45135940 - 45200890

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000187790 (version 78.38)

Entrez gene

57697

UniProt

Q8IYD8 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IYD8

Antibodypedia

FANCM antibodies
 

PROTEIN VIEW

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FANCM-001
 
FANCM-002
 
FANCM-003
 
FANCM-004
 
FANCM-005
 
FANCM-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FANCM-001 ENSP00000267430
ENST00000267430
Q8IYD8
Show all »
Show » Show » 2048 232.2 No 0
FANCM-002 ENSP00000450596
ENST00000556036
Q8IYD8
Show all »
Show » Show » 669 75.6 No 0
FANCM-003 ENSP00000442493
ENST00000542564
Q8IYD8
Show all »
Show » Show » 2022 229.3 No 0
FANCM-004 ENSP00000452033
ENST00000556250
H0YJS3
Show all »
Show » Show » 1564 178.1 No 0
FANCM-005 ENSP00000450632
ENST00000554809
Show » Show » 1016 114.8 No 0
FANCM-009 ENSP00000450797
ENST00000555484
H0YJ45
Show all »
Show » Show » 106 12.3 No 0