AMTN

GENE INFORMATION

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Gene name

AMTN (HGNC Symbol)

Synonyms

RSTI689, UNQ689

Description

Amelotin (HGNC Symbol)

Entrez gene summary

The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM, Mar 2008]

Chromosome

4

Cytoband

q13.3

Chromosome location (bp)

70518540 - 70532742

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000187689 (version 78.38)

Entrez gene

401138

UniProt

Q6UX39 (UniProt - Evidence at protein level)

neXtProt

NX_Q6UX39

Antibodypedia

AMTN antibodies
 

PROTEIN VIEW

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AMTN-001
 
AMTN-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AMTN-001 ENSP00000341013
ENST00000339336
Q6UX39
Show all »
Show » Show » 209 21.6 Yes 0
AMTN-002 ENSP00000422452
ENST00000504451
Q6UX39
Show all »
Show » Show » 208 21.5 Yes 0