CYP4F12

GENE INFORMATION

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Gene name

CYP4F12

Synonyms

Description

Cytochrome P450, family 4, subfamily F, polypeptide 12 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid. It can also catalyze the epoxidation of 22:6n-3 and 22:5n-3 polyunsaturated long-chain fatty acids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Chromosome

19

Cytoband

p13.12

Chromosome location (bp)

15672757 - 15697174

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186204 (version 78.38)

Entrez gene

66002

UniProt

neXtProt

Antibodypedia

CYP4F12 antibodies
 

PROTEIN VIEW

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CYP4F12-001
 
CYP4F12-006
 
CYP4F12-018
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP4F12-001 ENSP00000448998
ENST00000550308
Show » Show » 524 60.3 No 1
CYP4F12-006 ENSP00000321821
ENST00000324632
Show » Show » 524 60.3 No 1
CYP4F12-018 ENSP00000447922
ENST00000551607
Show » 70 7.7 No 0