CYP2R1

GENE INFORMATION

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Gene name

CYP2R1

Synonyms

Description

Cytochrome P450, family 2, subfamily R, polypeptide 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p15.2

Chromosome location (bp)

14877440 - 14892252

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000186104 (version 78.38)

Entrez gene

120227

UniProt

Q6VVX0 (UniProt - Evidence at protein level)

neXtProt

NX_Q6VVX0

Antibodypedia

CYP2R1 antibodies
 

PROTEIN VIEW

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CYP2R1-001
 
CYP2R1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP2R1-001 ENSP00000334592
ENST00000334636
Q6VVX0
Show all »
Show » Show » 501 57.4 Yes 0
CYP2R1-003 ENSP00000435484
ENST00000532378
E9PJT9
Show all »
Show » Show » 268 30.9 No 0