IRF7

GENERAL INFORMATION

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Gene name

IRF7

Gene description

Interferon regulatory factor 7

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Nuclear expression in most tissues, abundant in lymphatic organs.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA052757 , CAB017694
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Spleen

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

IRF7

Synonyms

Description

Interferon regulatory factor 7 (HGNC Symbol)

Entrez gene summary

IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

612553 - 615999

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000185507 (version 78.38)

Entrez gene

3665

UniProt

Q92985 (UniProt - Evidence at protein level)

neXtProt

NX_Q92985

Antibodypedia

IRF7 antibodies


PROTEIN BROWSER

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ENST00000330243
 
ENST00000348655
 
ENST00000397566
 
ENST00000397570
 
ENST00000397574
 
ENST00000525445
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IRF7-001 ENSP00000329411
ENST00000330243
Q92985
Show all »
Show » Show » 516 55.6 No 0
IRF7-002 ENSP00000380704
ENST00000397574
Q92985
Show all »
Show » Show » 503 54.3 No 0
IRF7-005 ENSP00000331803
ENST00000348655
Q92985
Show all »
Show » Show » 474 51.5 No 0
IRF7-006 ENSP00000434009
ENST00000525445
E9PSE3
Show all »
Show » Show » 397 42.3 No 0
IRF7-201 ENSP00000380697
ENST00000397566
Q92985
Show all »
Show » Show » 516 55.6 No 0
IRF7-202 ENSP00000380700
ENST00000397570
M9RSF4
Show all »
Show » Show » 487 52.8 No 0