MAFF

GENE INFORMATION

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Gene name

MAFF (HGNC Symbol)

Synonyms

hMafF

Description

V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Chromosome

22

Cytoband

q13.1

Chromosome location (bp)

38200767 - 38216511

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000185022 (version 78.38)

Entrez gene

23764

UniProt

Q9ULX9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9ULX9

Antibodypedia

MAFF antibodies
 

PROTEIN VIEW

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MAFF-001
 
MAFF-002
 
MAFF-003
 
MAFF-004
 
MAFF-201
 
MAFF-202
 
MAFF-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAFF-001 ENSP00000345393
ENST00000338483
Q9ULX9
Show all »
Show » Show » 164 17.8 No 0
MAFF-002 ENSP00000384094
ENST00000407965
Q9ULX9
Show all »
Show » Show » 164 17.8 No 0
MAFF-003 ENSP00000416493
ENST00000417948
B0QY70
Show all »
Show » Show » 126 14.3 No 0
MAFF-004 ENSP00000391589
ENST00000441709
B0QY71
Show all »
Show » Show » 93 10.7 No 0
MAFF-201 ENSP00000388882
ENST00000426621
Q9ULX9
Show all »
Show » Show » 164 17.8 No 0
MAFF-202 ENSP00000442060
ENST00000538320
Q9ULX9
Show all »
Show » Show » 164 17.8 No 0
MAFF-203 ENSP00000441482
ENST00000538999
Q9ULX9
Show all »
Show » Show » 135 14.6 No 0