SRY

GENE INFORMATION

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Gene name

SRY (HGNC Symbol)

Synonyms

TDF

Description

Sex determining region Y (HGNC Symbol)

Entrez gene summary

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008]

Chromosome

Y

Cytoband

p11.2

Chromosome location (bp)

2786855 - 2787699

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000184895 (version 78.38)

Entrez gene

6736

UniProt

Q05066 (UniProt - Evidence at protein level)

neXtProt

NX_Q05066

Antibodypedia

SRY antibodies
 

PROTEIN VIEW

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SRY-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SRY-001 ENSP00000372547
ENST00000383070
Q05066
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