EIF4ENIF1

GENERAL INFORMATION

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Gene name

EIF4ENIF1

Gene description

Eukaryotic translation initiation factor 4E nuclear import factor 1

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA001619 , HPA002078
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

EIF4ENIF1 (HGNC Symbol)

Synonyms

2610509L04Rik, 4E-T, Clast4, FLJ21601

Description

Eukaryotic translation initiation factor 4E nuclear import factor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

Chromosome

22

Cytoband

q12.2

Chromosome location (bp)

31436977 - 31496108

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000184708 (version 78.38)

Entrez gene

56478

UniProt

Q9NRA8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NRA8

Antibodypedia

EIF4ENIF1 antibodies


PROTEIN BROWSER

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ENST00000330125
 
ENST00000344710
 
ENST00000397518
 
ENST00000397520
 
ENST00000397523
 
ENST00000397525
 
ENST00000418321
 
ENST00000423097
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EIF4ENIF1-001 ENSP00000342927
ENST00000344710
Q9NRA8
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Show » Show » 811 88.2 No 0
EIF4ENIF1-002 ENSP00000328103
ENST00000330125
Q9NRA8
Show all »
Show » Show » 985 108.2 No 0
EIF4ENIF1-003 ENSP00000380659
ENST00000397525
Q9NRA8
Show all »
Show » Show » 985 108.2 No 0
EIF4ENIF1-005 ENSP00000380657
ENST00000397523
B1AKL4
Show all »
Show » Show » 961 105.5 No 0
EIF4ENIF1-006 ENSP00000405086
ENST00000423097
B1AKL5
Show all »
Show » 188 21.4 No 0
EIF4ENIF1-008 ENSP00000380654
ENST00000397520
B1AKL6
Show all »
Show » 63 7.3 No 0
EIF4ENIF1-009 ENSP00000380652
ENST00000397518
B1AKL6
Show all »
Show » 63 7.3 No 0
EIF4ENIF1-012 ENSP00000413690
ENST00000418321
B0QYZ7
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Show » Show » 239 26 No 0