NPW

GENE INFORMATION

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Gene name

NPW (HGNC Symbol)

Synonyms

PPL8

Description

Neuropeptide W (HGNC Symbol)

Entrez gene summary

The product of this gene is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

2009926 - 2020755

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183971 (version 78.38)

Entrez gene

283869

UniProt

Q8N729 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N729

Antibodypedia

NPW antibodies
 

PROTEIN VIEW

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NPW-001
 
NPW-002
 
NPW-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NPW-001 ENSP00000456974
ENST00000566435
H3BT17
Show all »
Show » 113 12.4 No 0
NPW-002 ENSP00000457009
ENST00000567649
H3BT42
Show all »
Show » 128 13.9 No 0
NPW-201 ENSP00000330070
ENST00000329610
Q8N729
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Show » Show » 165 18 Yes 0