CCR4

GENE INFORMATION

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Gene name

CCR4 (HGNC Symbol)

Synonyms

CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5

Description

Chemokine (C-C motif) receptor 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

p22.3

Chromosome location (bp)

32951574 - 32956349

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183813 (version 78.38)

Entrez gene

1233

UniProt

P51679 (UniProt - Evidence at protein level)

neXtProt

NX_P51679

Antibodypedia

CCR4 antibodies
 

PROTEIN VIEW

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CCR4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCR4-001 ENSP00000332659
ENST00000330953
P51679
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