FHL3

GENE INFORMATION

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Gene name

FHL3 (HGNC Symbol)

Synonyms

SLIM2

Description

Four and a half LIM domains 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Chromosome

1

Cytoband

p34.3

Chromosome location (bp)

37996770 - 38005606

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183386 (version 78.38)

Entrez gene

2275

UniProt

Q13643 (UniProt - Evidence at protein level)

neXtProt

NX_Q13643

Antibodypedia

FHL3 antibodies
 

PROTEIN VIEW

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FHL3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FHL3-001 ENSP00000362107
ENST00000373016
Q13643
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