FANCF

GENE INFORMATION

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Gene name

FANCF (HGNC Symbol)

Synonyms

FAF

Description

Fanconi anemia, complementation group F (HGNC Symbol)

Entrez gene summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group F. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p14.3

Chromosome location (bp)

22622519 - 22626787

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183161 (version 78.38)

Entrez gene

2188

UniProt

Q9NPI8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NPI8

Antibodypedia

FANCF antibodies
 

PROTEIN VIEW

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FANCF-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FANCF-001 ENSP00000330875
ENST00000327470
Q9NPI8
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